Early-life antibiotic use and gut microbiota

The early life gut microbiota and atopic disease

Background Asthma is the most prevalent of all childhood diseases and accounts for the majority of hospitalizations and school absences in children [1]. Current mouse model research has identified the early life gut microbiota as a potential therapeutic target for the prevention of asthma and atopic diseases [2-4]. We hypothesize that the early life gut microbiota could play a similar preventat...

Diversity of the gut microbiota and eczema in early life

BACKGROUND A modest number of prospective studies of the composition of the intestinal microbiota and eczema in early life have yielded conflicting results. OBJECTIVE To examine the relationship between the bacterial diversity of the gut and the development of eczema in early life by methods other than stool culture. METHODS Fecal samples were collected from 21 infants at 1 and 4 months of ...

Gut Microbiota and Neuropsychiatric Disorders

Gut Microbiota-Mediated Drug-Antibiotic Interactions.

Xenobiotic metabolism involves the biochemical modification of drugs and phytochemicals in living organisms, including humans and other animals. In the intestine, the gut microbiota catalyzes the conversion of hydrophilic drugs into absorbable, hydrophobic compounds through hydroxyzation and reduction. Drugs and phytochemicals are transformed into bioactive (sulfasalazine, lovastatin, and ginse...

Psychobiotics and Brain-Gut Microbiota Axis

Fermented foods containing probiotic bacteria have been used for many years to improve the health or treatment of some diseases. Nowadays, the Therapeutic properties of probiotics are becoming more and more obvious to everyone, insofar as in recent years, more attention has been paid to the potential relation between gut microbiota and mental health. Several studies have shown that intestinal m...